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Higher concentrations mean more Retatrutide per millilitre, requiring smaller injection volumes for a given dose
Trial-Reported Endpoints by Phase Trial Lancet 2021 Phase 2 Duration 26 weeks Population Overweight/obese, no T2D (n=706) Mean Weight Loss 10.8% at 4.5 mg vs 3.0% placebo Trial Lancet 2023 Phase 2 Duration 32 weeks Population T2D + obesity (n=92) Mean Weight Loss 8.1% cagrilintide alone
After 28 days, discard the vial regardless of how much medication remains
MACE = major adverse cardiovascular events
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